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1. SEARCH ARTICLES
2. ALPHABETICAL INDEX OF KEY TOPICS
2010
31. Hypertonic saline/epinephrine nebulisation for bronchiolitis
30. Are we doing enough to contain and eliminate rheumatic fever (RF)?
29. Placebo vs comparator drugs in paediatric drug trials
28. Anaemia in well under-fives in Venda
27. More on tight glycaemic control in the ICU
26. IQ, nutrition and burden of infectious disease
25. Intravenous Immune Globulin (IVIG): neonatal indications
24. Interventions for managing childhood and adolescent obesity
23. Renal care in private vs public dialysis facilities
22. NICE guidelines for treatment of neonatal jaundice
21. Organophosphates and Attention Deficit Hyperactivity Disorder (ADHD)
20. Vitamin A supplementation to reduce maternal mortality
19. Results of adenotonsillectomy for obstructive sleep apnoea in children
18. Malaria and co-infection with HIV
17. Frequency and effectiveness of bystander resuscitation for out-of-hospital cardiac arrest
16. Early dexamethasone (dex) to prevent bronchopulmonary dysplasia (BPD)
15. Safety of H1N1 vaccines
14. Mites, cockroaches and allergic rhinitis
13. Zinc and low osmolarity oral rehydration salts(ORS) for diarrhoea
12. The dilemma of vaginal vs. elective caesarean delivery after previous caesarean section (c/s)
11. Above- vs. below-elbow casts for distal forearm fractures
10. Bone mineral density (BMD) in cystic fibrosis (CF)
09. Respiratory administration of measles vaccine
08. Long-term outcome of children born with congenital anomalies
07. Safer childbirth: elective caesarean section (C/S) and pregnancy outcomes
06. Efficacy and safety of ibuprofen and paracetamol in children
05.Prevention of Hepatitis B (HBV) mother-to-child transmission (MTCT)
04. Rotavirus vaccine studied in Africa
03. Erythropoietin (Epo) for moderate hypoxic-ischaemic encephalopathy (HIE)
02. Susceptibility of H pylori to ‘usual’ antibiotics in South Africa
01. Rate of lung function deterioration in cystic fibrosis (CF)
2009
48. Melatonin for sleep disorders in children with attention deficit/hyperactivity disorder (ADHD)
47. Failure of chlorhexidine prophylaxis to prevent neonatal sepsis
46. Severe thrombocytopaenia and platelet transfusion in neonates
45. Aluminium exposure and long-term bone health
44. Manifestations of congenital anorectal malformations in adulthood
43. Biliary atresia update
42. Guidelines for neonatal resuscitation
41. Folate fortification – a good idea?
40. Effect of paracetamol on immunogenicity of childhood vaccines
39. Emergency Room management of paediatric head trauma
38. Tumour necrosis factor (TNFα) blockers and serious fungal infections
37. Adverse effects and HPV vaccine
36. Sildenafil for pulmonary hypertension (PulHT) in paediatrics
35. Vocal cord paralysis after ductal ligation in ELBW infants
34. Hypoplastic left heart syndrome – UK review
33. ‘Research opportunities’ in asthma management
32. Achieving Millennium Development Goals (MDGs) by 2015
31. Perventricular vs surgical closure of ventricular septal defects (VSDs)
30. High-field MRI for foetal post-mortem examination
29. Is it time to advocate Human Papillomavirus (HPV) immunization for all?
28. Severe acute malnutrition rates using NCHS vs WHO growth standards
27. Are we underdiagnosing congenital rubella in South Africa?
26. Is there a relationship between colic and gut colonization?
25. Iodine deficiency in South Africa
24. Vitamin D deficiency and development of diabetes
23. Progesterone to prevent preterm birth in twin pregnancies
22. Continuous end-tidal CO2 (ETCO2) monitoring: helpful and underutilized
21. What’s new in type 2 diabetes?
20. Does caesarean section (C/S) predispose to childhood asthma?
19. Neonatal resuscitation and cognition at 8 years of age
18. Concerns about clinical use of erythropoietin
17. Status of the fight against malaria
16. Threshold for initiation of Antiretroviral Therapy (ART)
15. Once-per-year bisphosphonate for glucocorticoid-induced osteoporosis
14. Interventions for pulmonary hypertension (PHT) in the newborn
13. Guidelines for administration of Growth Hormone (GH) in South Africa
12. Protection from noise in the Neonatal ICU (NICU)
11. Associations between the environment and childhood malignancies
10. Antibiotics, otitis media and mastoiditis
9. Tight glucose control in paediatric ICU patients
8. Adenovirus as a cause of obesity
7. 1½ to 2 year outcome after patent ductus (PDA) in infants below 1000 gm at birth
6. BCG immunization and HIV exposure – WHO guidelines followed or not?
5. Laparoscopic vs open surgery for pyloric stenosis
4. Assisted reproduction and neurodevelopment
3. Milk as a post-exercise rehydration fluid
2. Cisapride for reflux in neonates and children
1. Antenatal steroids for lung maturation: how many courses?
2008
48. What is happening to antenatal HIV prevalence rates in South Africa?
47. Helicobacter as a cause of refractory iron deficiency anaemia in paediatrics
46. Early antiretroviral therapy (ART) better than expectant therapy in HIV-infected infants
45. A new and accurate genetic test for unbalanced genomic defects
44. Should male circumcision be incorporated into anti-HIV/AIDS policies?
43. More on triage for admission in first two months of life
42. Facts about melamine
41. 7-year follow up of antibiotics for PROM and preterm labour
40. Migraine update
39. Possible adverse effects of erythropoietin-induced correction of anaemia
38. Cerebral oedema in diabetic ketoacidosis – an update
37. Does paracetamol cause asthma?
36. Cladophialophora bantiana as a cause of cerebral abscess
35. Risks and consequences of nephrocalcinosis in premature infants
34. More on outcomes after assisted reproduction
33. Cardiac monitoring in children after household electrical injury
32. Mortality after febrile seizures
31. Postnatal infections and white matter injury in premature infants
30. Outcome after assisted reproduction
29. Pro- and anti-coagulatory factor deficiencies with valproate
28. Update on haemolytic uraemic syndrome (HUS)
27. Hazards of co-administration of IV ceftriaxone and IV calcium-containing products
26. Delayed introduction of cow’s milk and/or solids and development of allergic disease
25. Questionable value of control measures for house dust mites
24. Health economics and clinical practice
23. Orphan drugs and orphan diseases
22. Hypothermia for prevention and management of neurological injury
21. Prophylaxis against complications of preterm birth
20. Antibody to aquaporin-4 (AQP4) as a marker of certain demyelinating diseases
19. Neurodevelopmental outcome in paediatric HIV/AIDS
18. Is ibuprofen better than indomethacin for ductal closure?
17. NICE guidelines on antibiotic prophylaxis to prevent infective endocarditis
16. Significance of nucleated red cells during the first week of life
15. Early dexamethasone and neurodevelopmental outcome at school age
14. Lancet calls for withdrawal of cough medicines for children
13. Emergence of fluoroquinolone-resistant Strep pneumoniae in children in South Africa
12. Maternal peripartum cardiomyopathy (PPCM)
11. Risk of atopic disease and diabetes after caesarean section
10. More evidence of maternal microchimerism in neonatal biliary atresia
9. Early pulse oximetry accurately predicts congenital heart disease
8. Risk factors for metabolic syndrome in later life
7. Intravenous immunoglobulin (IVIG) for immune haemolysis and hyperbilirubinaemia
6. New treatment for chronic immune thrombocytopaenia
5. Practice variations and questions around indomethacin for PDA closure in VLBW infants
4. Iron and folate or multiple micronutrients for pregnant women in high-risk environments?
3. Triage on the basis of clinical signs in infants of <2 months of age
2. Update on preterm delivery at <37 weeks
1. Answers or more questions on the role of polymorphism in response of asthma to β2-agonists?
2007
47. Pre-implantation aneuploidy screening may reduce the chances of successful pregnancy
46. Analysis of neonatal ventilation strategies
45. Hypotonic vs isotonic maintenance IV fluids in hospitalized children
44. Role of heme oxygenase-1 (HO-1) in apoptosis and inflammation
43. Steroids for meconium aspiration syndrome (MAS)
42. Iron deficiency and stroke – patients are not the only slow learners
41. Insights into anorexia nervosa
40. Shorter sleep duration is associated with overweight
39. Physiotherapy for HIV exposed and affected infants
38. Is zinc the missing link in combating micronutrient malnutrition in developing countries?
37. Diabetes and cerebral oedema
36. Maternal vitamin D deficiency and neonatal seizures
35. Is adult COPD sometimes a consequence of impaired foetal and/or neonatal lung development?
34. Non-pressor effects of pressors
33. Sunlight and melanoma – what advice for parents and children?
32. Aquaporin studies relevant to the neonate
31. Probiotics for treatment of acute diarrhea
30. Newly-identified and/or -emerging respiratory viruses in children
29. Rotavirus update
28. Urinary cytokines to diagnose acute and chronic renal problems
27. Placental lesions as predictors of cerebral palsy (CP) and abnormal cognitive function
26. Cancer risks in HIV-positive children and adolescents
25. Vitamin A supplementation: too much, too little or just right?
24. Maternal microchimerism in biliary atresia
23. Pacifiers/dummies reduce the incidence of cot death/SIDS
22. Parvovirus B19 and joint disease
21. Low-dose anti-platelet agents for prevention of pre-eclampsia
20. The ‘fungins’ for treatment of invasive and/or resistant fungal infection
19. Do probiotics prevent necrotising enterocolitis (NEC)?
18. Permissive hypercapnoea increasingly supported by research
17. Time to revise WHO guidelines for treatment of pneumonia in infants
16. Update on management of hypoxic ischaemic encephalopathy (HIE)
15. Cell death and damage in paediatric lung disease
14. Finally, the definitive KZN data on exclusive breast feeding and HIV
13. Does melatonin play a role in development of idiopathic scoliosis?
12. Update on Henoch-Schonlein purpura (HSP)
11. Multicentre trial of activated protein C for paediatric sepsis – a step forward or back?
10. Proximity to traffic and long-term effects on lung development/function
09. Turnaround on seafood consumption during pregnancy
08. What are the neurodevelopmental sequelae of early exposure to dexamethasone?
07. More on optimal Hb levels in chronic renal failure
06. Pyloric stenosis (PS) after early exposure to azithromycin
05. Are there alternatives to nitric oxide (NO) for neonatal pulmonary hypertension?
04. Prenatal treatment for toxoplasmosis following maternal seroconversion
03. Risk of cerebral palsy (CP) in children born below 1500g
02. Clinical and financial costs of erythropoietin (Epo) for anaemia of chronic renal disease
01. A better method of oxime administration for organophosphate poisoning?
2006
48.
Spontaneous intestinal perforation (SIP) in VLBW neonates
47.
Cardiovascular risk exists with both specific inhibitors and ‘historical’ NSAIDS
46.
Growing understanding of the role of RNA editing
45.
Response to a programme of identifying avoidable maternal deaths
44.
Direct and indirect meta-analysis of drug trials
43.
The incretin system and possible role in managing type-2 diabetes
42.
Insulin and the INS VNTR genotype
41.
Effect of inter-pregnancy weight gain on mother and foetus
40.
When to use antibiotics in acute otitis media (AOM)
39.
A quasi-syndromic approach to partial seizures
38.
Guidelines for phototherapy and exchange transfusion
37.
Neuropsychiatric manifestations of streptococcal infections
36.
More on fortifying feeds for infants and children
35.
Recent developments in immunology
34.
Malaria, parvovirus and anaemia
33.
Micronutrients for childhood pneumonia in developing countries
32.
Vigilance probably still necessary in respect of paediatric
consequences of mercury intake
31.
Some pitfalls in the prescription and/or acquisition of medicines
in the 21st century
30.
More on nitric oxide (NO) for neonatal respiratory distress
29.
Are statins analogues of vitamin D?
28.
Low dairy intake in childhood and excess body fat in adolescence
27.
Possibility of chikungunya fever in visitors to Mauritius
26.
Neuropsychiatric disorders and streptococcal infections –
the case for PANDAS
25.
Nitric oxide (NO), L-arginine and PDE5 inhibition in cystic fibrosis (CF)
24.
Report of the 2005 WHO global survey on caesarean section rates
and perinatal outcome
23.
The more we immunise the more we learn about immunisation –
Pertussis 2006
22.
Anything new in diagnosis and management of infantile colic?
21.
Inadequate data on long-term outcomes in Paediatrics
20.
Interplay between gestational age, anaemia and retinopathy of prematurity
(ROP)
19.
CNEP (continuous negative extrathoracic pressure ventilation) vindicated
18.
Current thoughts on aetiology and prevention of bronchopulmonary dysplasia
(BPD)
17.
Activated protein C for meningococcaemia with purpura fulminans
16.
Does sodium cromoglycate lower the risk for asthma in school-age children?
15.
Turning the oxyhaemoglobin dissociation curve around
14.
More on current concepts around diabetes
13.
Immunotherapeutic approaches to Type 1 Diabetes (T1D)
12.
Complexity of the immune responses in TB
11.
Rheumatic fever control probably requires more education, advocacy and
activism
10.
Does kangaroo mother care (KMC) reduce morbidity and mortality in LBW
infants?
9.
Laparoscopic antireflux surgery in infants and children
8.
Effect of handwashing on child health
7.
Early signs of meningococcal disease in Paediatrics
6.
Steroid treatment of refractory hypotension in VLBW neonates
5.
Intracranial endoscopy - its role in paediatrics
4.
Routine iron supplementation may be harmful in malaria-endemic areas
3.
Does intrauterine programming affect bone status in childhood?
2.
Endocrine effects of valproate are uncommon in females with childhood-onset
epilepsy
1.
Sustainability of exclusive breast feeding in Baby Friendly Hospitals
2005
48.
Single-dose treatment for paediatric cholera
47.
ART and lactic acidosis in paediatrics
46.
Long term follow up of early nutritional and psychosocial intervention
in stunted children
45.
Critical Issues around development of HIV vaccines
44.
Do benefits of DDT for malaria prevention outweigh the risks?
43.
Current understanding of Guillain-Barre syndrome
42.
Aquaporins and the kidney
41.
Aquaporins and the brain
40.
Nitric oxide results may not be as favourable as originally claimed
39.
Issues around HIV risk during pregnancy and syndromic treatment of STIs
38.
What should we be doing to prevent adult disease possibly 'programmed'
by LBW/IUGR?
37.
Hyperbilirubinaemia under control or is there still place for a new treatment?
36.
Partitioning the base deficit assists in understanding aetiology of acid-base
disturbances
35.
Going beyond the base deficit to predict mortality
34.
Artesunate vs quinine for severe falciparum malaria
33.
For some of those who thought they knew everything about lipid mediators
32.
Early neonatal hearing screening followed up for 7-9 years
31.
GINA, the Global Initiative for Asthma
30.
Even more to polio eradication than met the eye in 1988
29.
Current thoughts on an old disease
28.
Buccal midazolam better than rectal diazepam for emergency control of
seizures in children
27.
Debate around the appropriateness of the 1000g cutoff for prems in the
public sector
26.
Juvenile idiopathic arthritis (JIA) and heat shock proteins
25.
Acute renal failure (ARF) after treatment with NSAIDS
24.
Pleiotropic actions of erythropoietin (Epo)
23.
Liggins Institute sets the standard for perinatal research
22.
An alternative to surgery for sleep apnoea?
21.
The impact of climate changes on health and disease
20
Aortic changes in IUGR and relationship to the Barker hypothesis
19.
Approaches
to malaria prevention and treatment in Africa
18.
BPD in the 21st century
17.
Patient symptoms better than peak flows for asthma exacerbation risk
16.
Patient safety receiving attention in the USA and abroad
15.
Watch this 'spase'
14.
Adiponectin and renal disease
13.
Meeting the Millenium Development Goals - focus on neonatal survival
12.
Effects of maternal micronutrient supplementation on fetal growth
11.
Development of 'designer glucorticoids'
10.
Update on pre-eclampsia (PE)
9.
Effects of altitude on pharmacokinetics and pharmacodynamics
8.
Head cooling for treatment of neonatal encephalopathy
7.
Malaria and HIV
6.
Vitamin D deficiency in early infancy
5. Ibuprofen perhaps not as safe as
one thought for PDA prophylaxis in preterm infants
4. Use of a rapid enzyme-linked immunospot
assay for diagnosis of TB in children?
3. More on theophylline and its role
in asthma?
2. Which children with ADHD are likely
to respond to methylphenidate (MP)?
1. Renewed interest in methyl xanthines
2004
48. Will COX-2 inhibitors survive the
current focus of attention?
47. Do we pay enough attention to drug
interactions?
46. Hepatitis C in HIV infection presents
new therapeutic and cost amplification loops
45. More options for treatment of paediatric
allergy
44. Anti-leukotrienes as monotherapy
in the young asthmatic
43. Ups and downs of IMCI?
42. Treatment for vesico-ureteric reflux
(VUR) - are the waters getting clearer?.
41.
Targeting bronchodilators - can one identify responders vs non-responders?
40. Procalcitonin (PCT) as a marker
of neonatal sepsis.
39. Malaria vaccines - when?
38. More on neonatal resuscitation
using air vs oxygen
37. Radiofrequency treatment for obstructive
adeno-tonsillar hypertrophy
36. ENT procedures for recurrent tonsillitis
better than medical therapy?
35. Helicobacter pylori infection in
Paediatrics
34. What has Mycobacterium avium paratuberculosis
to do with inflammatory bowel disease?
33. Simple interventions may achieve
significant results in birth outcomes in underdeveloped areas
32. HMG-CoA reductase inhibitors: anti-inflammatory
potentiation in auto-immune diseases
31. Oral rehydration solutions containing
non-digestible carbohydrates in the treatment of acute infectious diarrhoea
30. Free water handling in seriously
ill children
29. Marginal effect of second opinion
on elective caesarean section (c/s) rates
28. Meningococcal conjugate vaccine:
a valuable addition to the immunization schedule
27. Possible adverse effects of postnatal growth acceleration
26. Epo-alpha for chronic renal disease only rarely induces antibodies
25. Transmission and progression of HIV/AIDS
24.
Cervical cerclage for short cervix does not prevent preterm delivery
23. New use for old drugs in the treatment
of uncomplicated falciparum malaria
22. Rotavirus vaccine: beyond the simple
association with intussusception
21. Autoantibodies in pregnancy as predictors
of disease
20. Which guidelines influence clinical practice?
19. Foetal determinants of adult disease
18.
How to identify future tolerance in children with milk allergy
17. Role of Wall Teichoic Acid (WTA)
in adherence of Staph aureus to nasal mucosa
16. SSRI's during pregnancy appear
to be safe for the fetus and neonate.
15. No real clarity on aetiology of eosinophilic
gastroenteritis (EGE)
14.
Enthusiastic reports of immune modulatory treatment of atopic dermatitis
13. More about the relationship between Hepatitis
C (HCV) and Diabetes Mellitus
12. Reversal of syphilis:HIV infection
ratios in antenatal clinic attendees
11. Role for insulin in recovery and
repair
10. New Onset Diabetes Mellitus (NODM)
after Tacrolimus
9.
Evidence that hypertension is an inflammatory disorder
8.
Pancreatic beta cells are sensitive to treatment of ALL
(acute lymphoblastic leukaemia)
7. How malaria affects the placenta
6. Air pollution and the respiratory
allergic response
5. Role of interleukin 6 (IL-6) in
meningococcal shock
4.
Emerging role for vitamin K in treatment of osteoporosis?
3. Steroid sprays not all equal in
the treatment of allergic rhinitis
2.
Erythropoietin (Epo) as a cause of antibody-mediated pure red cell aplasia
(PRCA)
1.
Is resistin a mediator of gestational diabetes?
2003
48. Caesarean delivery appears to be
associated with increased risk of subsequent stillbirth
47. How good is BAD for diagnosis of
causative organism in meningitis?
46. COX-2 inhibitors may not be safe
for tocolysis
45. SLIT vs SCIT for management of allergic
disease
44. Expanded role of leptin
42.Glimmer of light into aetiology of
neonatal cholestasis?
41. Nevirapine vs Zidovudine for prevention
of mother-to-child transmission of HIV
40.
Ischaemic tolerance: does it occur in the foetus?
39. Higher carbonated soft drink consumption
associated with lower bone density
38. Acute Lymphoblastic Leukaemia may
have similar outcome in black and white children
37. Electronic Foetal Monitoring: the debate continues
36. Pneumococcal vaccine better for
prevention of acute otitis media than for cure?
35. House dust mite allergen avoidance
different in adults vs children?
34. Hyperbaric oxygen treatment - scientific
research is lacking
33. Inappropriate outpatient use of
flouroquinolones
32.
Questions around use of bisphosphonates for paediatric bone disease
31.
Possible consequences of TNF (tumour necrosis factor) suppression
30.
Another strategy to limit mother-to-child transmission of HIV
29.
Intravenous IgG (IVIG) appears to have a place in management of severe
asthma
28.
Beckwith-Wiedemann Syndrome (BWS) more likely following assisted reproduction?
27. Early-onset neonatal group B streptococcal
(GBS) sepsis probably underestimated
26.
Chlamydia should be regarded as an organism affecting the paediatric population
25. Inhaled magnesium sulphate enhances
bronchodilatation in severe asthma in adults
24. Prevention of preterm birth due
to vaginosis
23. Inhaled steroids better than leukotriene
antagonists for asthma maintenance
22. Most HIE appears to be of recent
onset
21. Lead toxicity - still a significant
risk in children
20. Does early steroid therapy prevent
permanent airway damage in asthma?:
19.
Do seizures in childhood have long term consequences?
18.
Room air for resuscitation of asphyxiated neonates:
17. Erythropoietin as neuroprotectant:
16. Bronchiolitis in infancy:
15. Passive immunisation of infants
at risk for bronchiolitis:
14. COX-3: specific for pain and temperature
effects?:
13. Hyperglycaemia and foetal malformation:
12. Thrombocytopenia in the NICU:
11. Ghrelin in the foetus, neonate
and infant:
10. Endocrine and metabolic control
of appetite:
9. Adiponectin and protection against
type 2 diabetes mellitus:
8. Activated protein C for severe sepsis:
7. Hyperbaric oxygen for carbon monoxide
poisoning:
6. Nitric oxide and malaria:
5. Sildenafil for pulmonary hypertension:
4. Erythromycin and pyloric stenosis:
3. Rotavirus vaccine and intussusception:
2. Anaemia of Chronic Disease:
1. Exhaled nitric oxide as a marker
of airway inflammation:
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